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Beta(2)-Adrenergic Receptor Homodimers: Role of transmembrane domain 1 and helix 8 in dimerization and cell surface expression

Even though there are hundreds of reports in the published literature supporting the hypothesis that G protein-coupled receptors (GPCR) form and function as dimers this remains a highly controversial area of research and mechanisms governing homodimer formation are poorly understood. Crystal structu...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Parmar, Vikas K., Grinde, Ellinor, Mazurkiewicz, Joseph E., Herrick-Davis, Katharine
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474359/
https://ncbi.nlm.nih.gov/pubmed/27993566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2016.12.007
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