Clinical Pharmacogenetics Implementation Consortium (CPIC®) Guideline for CYP2C19 and Voriconazole Therapy

Voriconazole, a triazole antifungal agent, demonstrates wide interpatient variability in serum concentrations, due in part to variant CYP2C19 alleles. Individuals who are CYP2C19 ultrarapid metabolizers have decreased trough voriconazole concentrations, delaying achievement of target blood concentra...

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Bibliographic Details
Published in:Clin Pharmacol Ther
Main Authors: Moriyama, Brad, Owusu Obeng, Aniwaa, Barbarino, Julia, Penzak, Scott R., Henning, Stacey A., Scott, Stuart A., Agúndez, José A. G., Wingard, John R., McLeod, Howard L, Klein, Teri E., Cross, Shane, Caudle, Kelly E., Walsh, Thomas J.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474211/
https://ncbi.nlm.nih.gov/pubmed/27981572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.583
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