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Molecular Pathways: Oncologic Pathways and Their Role in T-cell Exclusion and Immune Evasion- A New Role for the AXL Receptor Tyrosine Kinase

With the clinical impact of CTLA-4 and PD-1/PD-L1 immune checkpoint therapies, widespread interest in cancer immunotherapy has been ignited. However, the rate and extent of clinical responses to approved therapies are limited and often non-existent in many solid tumors. This is partially because imm...

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Опубликовано в: :Clin Cancer Res
Главные авторы: Aguilera, Todd A., Giaccia, Amato J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474155/
https://ncbi.nlm.nih.gov/pubmed/28289089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0189
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