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Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo
Shadoo (Sho), a member of prion protein family, has been shown to prevent embryonic lethality in Prnp (0/0) mice and to be reduced in the brains of rodents with terminal prion diseases. Sho can also affect PrP structural dynamics and can increase the prion conversion into its misfolded isoform (PrP(...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5473912/ https://ncbi.nlm.nih.gov/pubmed/28623368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03969-2 |
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