Hif-1α Knockdown Reduces Glycolytic Metabolism and Induces Cell Death of Human Synovial Fibroblasts Under Normoxic Conditions

Increased glycolysis and HIF-1α activity are characteristics of cells under hypoxic or inflammatory conditions. Besides, in normal O(2) environments, elevated rates of glycolysis support critical cellular mechanisms such as cell survival. The purpose of this study was to analyze the contribution of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Del Rey, Manuel J., Valín, Álvaro, Usategui, Alicia, García-Herrero, Carmen M., Sánchez-Aragó, María, Cuezva, José M., Galindo, María, Bravo, Beatriz, Cañete, Juan D., Blanco, Francisco J., Criado, Gabriel, Pablos, José L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473902/
https://ncbi.nlm.nih.gov/pubmed/28623342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03921-4
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