Stepwise pH-responsive nanoparticles for enhanced cellular uptake and on-demand intracellular release of doxorubicin

Physicochemical properties, including particle size, zeta potential, and drug release behavior, affect targeting efficiency, cellular uptake, and antitumor effect of nanocarriers in a formulated drug-delivery system. In this study, a novel stepwise pH-responsive nanodrug delivery system was develope...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Chen, Wei-liang, Li, Fang, Tang, Yan, Yang, Shu-di, Li, Ji-zhao, Yuan, Zhi-qiang, Liu, Yang, Zhou, Xiao-feng, Liu, Chun, Zhang, Xue-nong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2017
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473598/
https://ncbi.nlm.nih.gov/pubmed/28652730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S129748
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