A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

Diarrhoeal disease is responsible for 8.6% of global child mortality. Recent epidemiological studies found the protozoan parasite Cryptosporidium to be a leading cause of paediatric diarrhoea, with particularly grave impact on infants and immunocompromised individuals. There is neither a vaccine nor...

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Publicado no:Nature
Main Authors: Manjunatha, Ujjini H., Vinayak, Sumiti, Zambriski, Jennifer A., Chao, Alexander T., Sy, Tracy, Noble, Christian G., Bonamy, Ghislain M. C., Kondreddi, Ravinder R., Zou, Bin, Gedeck, Peter, Brooks, Carrie F., Herbert, Gillian T., Sateriale, Adam, Tandel, Jayesh, Noh, Susan, Lakshminarayana, Suresh B., Lim, Siau H., Goodman, Laura B., Bodenreider, Christophe, Feng, Gu, Zhang, Lijun, Blasco, Francesca, Wagner, Juergen, Leong, F. Joel, Striepen, Boris, Diagana, Thierry T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473467/
https://ncbi.nlm.nih.gov/pubmed/28562588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22337
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