HDAC Inhibitor Conjugated Polymeric Prodrug Micelles for Doxorubicin Delivery

Amphiphilic diblock copolymers bearing histone deacetylase inhibitors (HDACi) (4-phenyl butyric acid and valproic acid) were synthesized by the ring-opening polymerization of γ-4-phenylbutyrate-ε-caprolactone (PBACL), γ-valproate-ε-caprolactone (VPACL), and ε-caprolactone (CL) from a poly(ethylene g...

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Bibliografiske detaljer
Udgivet i:J Mater Chem B Mater Biol Med
Main Authors: Senevirathne, Suchithra A., Washington, Katherine E., Miller, Jason B., Biewer, Michael C., Oupicky, David, Siegwart, Daniel J., Stefan, Mihaela C.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473365/
https://ncbi.nlm.nih.gov/pubmed/28630710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6TB03038F
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