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Experience-dependent epigenomic reorganization in the hippocampus

Using a hippocampus-dependent contextual threat learning and memory task, we report widespread, coordinated DNA methylation changes in CA1 hippocampus of Sprague-Dawley rats specific to threat learning at genes involved in synaptic transmission. Experience-dependent alternations in gene expression a...

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發表在:Learn Mem
Main Authors: Duke, Corey G., Kennedy, Andrew J., Gavin, Cristin F., Day, Jeremy J., Sweatt, J. David
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473107/
https://ncbi.nlm.nih.gov/pubmed/28620075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.045112.117
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