Reorganization of the host epigenome by a viral oncogene

Adenovirus small e1a oncoprotein causes ∼70% reduction in cellular levels of histone H3 lysine 18 acetylation (H3K18ac). It is unclear, however, where this dramatic reduction occurs genome-wide. ChIP-sequencing revealed that by 24 h after expression, e1a erases 95% of H3K18ac peaks in normal, contac...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Ferrari, Roberto, Su, Trent, Li, Bing, Bonora, Giancarlo, Oberai, Amit, Chan, Yvonne, Sasidharan, Rajkumar, Berk, Arnold J., Pellegrini, Matteo, Kurdistani, Siavash K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2012
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396363/
https://ncbi.nlm.nih.gov/pubmed/22499665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.132308.111
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller