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Heterologous expression of an α-amylase inhibitor from common bean (Phaseolus vulgaris) in Kluyveromyces lactis and Saccharomyces cerevisiae

BACKGROUND: Phaseolamin or α-amylase inhibitor 1 (αAI) is a glycoprotein from common beans (Phaseolus vulgaris L.) that inhibits some insect and mammalian α-amylases. Several clinical studies support the beneficial use of bean αAI for control of diabetes and obesity. Commercial extracts of P. vulgar...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Brain-Isasi, Stephanie, Álvarez-Lueje, Alejandro, Higgins, Thomas Joseph V.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472880/
https://ncbi.nlm.nih.gov/pubmed/28619052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0719-4
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