INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers

ATP-dependent chromatin remodellers modulate nucleosome dynamics by mobilizing or disassembling nucleosomes, as well as altering nucleosome composition. These chromatin remodellers generally function by translocating along nucleosomal DNA at the H3–H4 interface of nucleosomes. Here we show that, unl...

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Pubblicato in:Nat Commun
Autori principali: Brahma, Sandipan, Udugama, Maheshi I., Kim, Jongseong, Hada, Arjan, Bhardwaj, Saurabh K., Hailu, Solomon G., Lee, Tae-Hee, Bartholomew, Blaine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472786/
https://ncbi.nlm.nih.gov/pubmed/28604691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15616
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