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Removal of H2A.Z by INO80 promotes homologous recombination

The mammalian INO80 remodelling complex facilitates homologous recombination (HR), but the mechanism by which it does this is unclear. Budding yeast INO80 can remove H2A.Z/H2B dimers from chromatin and replace them with H2A/H2B dimers. H2A.Z is actively incorporated at sites of damage in mammalian c...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Alatwi, Hanan E, Downs, Jessica A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552491/
https://ncbi.nlm.nih.gov/pubmed/26142279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540330
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