The Nogo-B receptor promotes Ras plasma membrane localization and activation

The localization of prenylated Ras at the plasma membrane promotes activation of Ras by receptor tyrosine kinases and stimulates oncogenic signaling by mutant Ras. The Nogo-B receptor (NgBR) is a transmembrane receptor that contains a conserved hydrophobic pocket. Here, we demonstrate that the NgBR...

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發表在:Oncogene
Main Authors: Zhao, Baofeng, Hu, Wenquan, Kumar, Suresh, Gonyo, Patrick, Rana, Ujala, Liu, Zhong, Wang, Bei, Duong, William Q., Yang, Zhe, Williams, Carol L., Miao, Qing R.
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472485/
https://ncbi.nlm.nih.gov/pubmed/28068323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.484
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