Nogo-B receptor deficiency increases LXRα nuclear translocation and hepatic lipogenesis via an AMPKα-dependent pathway

Nogo-B receptor (NgBR) was identified as a specific receptor for binding Nogo-B, and is essential for the stability of Niemann-Pick type C2 protein (NPC2) and NPC2-dependent cholesterol trafficking. Here, we report that NgBR expression levels decrease in the fatty liver and that NgBR plays previousl...

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Bibliografiska uppgifter
I publikationen:Hepatology
Huvudupphovsmän: Hu, Wenquan, Zhang, Wenwen, Chen, Yuanli, Rana, Ujala, Teng, Ru-jeng, Duan, Yajun, Liu, Zhong, Zhao, Baofeng, Foeckler, Jamie, Weiler, Hartmut, Kallinger, Rachel E., Thomas, Michael J., Zhang, Kezhong, Han, Jihong, Miao, Qing Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074877/
https://ncbi.nlm.nih.gov/pubmed/27480224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28747
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