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Substrate transport and anion permeation proceed through distinct pathways in glutamate transporters

Advances in structure-function analyses and computational biology have enabled a deeper understanding of how excitatory amino acid transporters (EAATs) mediate chloride permeation and substrate transport. However, the mechanism of structural coupling between these functions remains to be established...

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Publicat a:eLife
Autors principals: Cheng, Mary Hongying, Torres-Salazar, Delany, Gonzalez-Suarez, Aneysis D, Amara, Susan G, Bahar, Ivet
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472439/
https://ncbi.nlm.nih.gov/pubmed/28569666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25850
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