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Partitioning Circadian Transcription by SIRT6 Leads to Segregated Control of Cellular Metabolism
Circadian rhythms are intimately linked to cellular metabolism. Specifically, the NAD(+)-dependent deacetylase SIRT1, the founding member of the sirtuin family, contributes to clock function. Whereas SIRT1 exhibits diversity in deacetylation targets and subcellular localization, SIRT6 is the only co...
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| 出版年: | Cell |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5472354/ https://ncbi.nlm.nih.gov/pubmed/25083875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.050 |
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