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Partitioning Circadian Transcription by SIRT6 Leads to Segregated Control of Cellular Metabolism

Circadian rhythms are intimately linked to cellular metabolism. Specifically, the NAD(+)-dependent deacetylase SIRT1, the founding member of the sirtuin family, contributes to clock function. Whereas SIRT1 exhibits diversity in deacetylation targets and subcellular localization, SIRT6 is the only co...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Masri, Selma, Rigor, Paul, Cervantes, Marlene, Ceglia, Nicholas, Sebastian, Carlos, Xiao, Cuiying, Roqueta-Rivera, Manuel, Deng, Chuxia, Osborne, Timothy F., Mostoslavsky, Raul, Baldi, Pierre, Sassone-Corsi, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472354/
https://ncbi.nlm.nih.gov/pubmed/25083875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.050
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