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Modeling In Vivo Pharmacokinetics and Pharmacodynamics of Moxifloxacin Therapy for Mycobacterium tuberculosis Infection by Using a Novel Cartridge System

To study the efficacy of moxifloxacin treatment for tuberculosis, we utilized a novel cartridge system to simulate in vivo pharmacokinetics. We found this system to be a robust method for modeling in vivo pharmacokinetics and present data supporting the utility of intermittent moxifloxacin treatment...

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Detalhes bibliográficos
Main Authors: Ginsburg, Amy Sarah, Lee, Jin, Woolwine, Samuel C., Grosset, Jacques H., Hamzeh, Fayez M., Bishai, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547230/
https://ncbi.nlm.nih.gov/pubmed/15673788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.2.853-856.2005
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