The Aspergillus fumigatus CrzA Transcription Factor Activates Chitin Synthase Gene Expression during the Caspofungin Paradoxical Effect

Aspergillus fumigatus is an opportunistic fungal pathogen that causes invasive aspergillosis (IA), a life-threatening disease in immunocompromised humans. The echinocandin caspofungin, adopted as a second-line therapy in combating IA, is a β-1,3-glucan synthase inhibitor, which, when used in high co...

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Publicado en:mBio
Main Authors: Ries, Laure Nicolas Annick, Rocha, Marina Campos, de Castro, Patrícia Alves, Silva-Rocha, Rafael, Silva, Roberto Nascimento, Freitas, Fernanda Zanolli, de Assis, Leandro José, Bertolini, Maria Célia, Malavazi, Iran, Goldman, Gustavo H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472186/
https://ncbi.nlm.nih.gov/pubmed/28611248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00705-17
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