Overexpressed PRAME is a potential immunotherapy target in sarcoma subtypes

BACKGROUND: PRAME (preferentially expressed antigen in melanoma), a member of the cancer-testis antigen family, has been shown to have increased expression in solid tumors, including sarcoma, and PRAME-specific therapies are currently in development for other cancers such as melanoma. METHODS: To ma...

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Veröffentlicht in:Clin Sarcoma Res
Hauptverfasser: Roszik, Jason, Wang, Wei-Lien, Livingston, John A., Roland, Christina L., Ravi, Vinod, Yee, Cassian, Hwu, Patrick, Futreal, Andrew, Lazar, Alexander J., Patel, Shreyaskumar R., Conley, Anthony P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471883/
https://ncbi.nlm.nih.gov/pubmed/28630682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13569-017-0077-3
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