Compensatory and decompensatory alterations in cardiomyocyte Ca(2+) dynamics in hearts with diastolic dysfunction following aortic banding

KEY POINTS: At the cellular level cardiac hypertrophy causes remodelling, leading to changes in ionic channel, pump and exchanger densities and kinetics. Previous studies have focused on quantifying changes in channels, pumps and exchangers without quantitatively linking these changes with emergent...

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Publicat a:J Physiol
Autors principals: Gattoni, Sara, Røe, Åsmund Treu, Aronsen, Jan Magnus, Sjaastad, Ivar, Louch, William E., Smith, Nicolas P., Niederer, Steven A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Cardiac Excitation Contraction Coupling and Calcium Signalling
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471387/
https://ncbi.nlm.nih.gov/pubmed/28542952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273879
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