Fluconazole-Induced Ploidy Change in Cryptococcus neoformans Results from the Uncoupling of Cell Growth and Nuclear Division

Cryptococcus neoformans is a pathogenic yeast that causes lethal cryptococcal meningitis in immunocompromised patients. One of the challenges in treating cryptococcosis is the development of resistance to azole antifungals. Previous studies linked azole resistance to elevated numbers of copies of cr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:mSphere
Main Authors: Altamirano, Sophie, Fang, Diana, Simmons, Charles, Sridhar, Shreyas, Wu, Peipei, Sanyal, Kaustuv, Kozubowski, Lukasz
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471349/
https://ncbi.nlm.nih.gov/pubmed/28630940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00205-17
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