Fluconazole-Induced Ploidy Change in Cryptococcus neoformans Results from the Uncoupling of Cell Growth and Nuclear Division

Cryptococcus neoformans is a pathogenic yeast that causes lethal cryptococcal meningitis in immunocompromised patients. One of the challenges in treating cryptococcosis is the development of resistance to azole antifungals. Previous studies linked azole resistance to elevated numbers of copies of cr...

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Publicat a:mSphere
Autors principals: Altamirano, Sophie, Fang, Diana, Simmons, Charles, Sridhar, Shreyas, Wu, Peipei, Sanyal, Kaustuv, Kozubowski, Lukasz
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471349/
https://ncbi.nlm.nih.gov/pubmed/28630940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00205-17
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