Intraoperative imaging of hepatic cancers using γ-glutamyltranspeptidase-specific fluorophore enabling real-time identification and estimation of recurrence

γ-Glutamyltranspeptidase (GGT) is upregulated in a variety of human cancers including primary and secondary hepatic tumors. This motivated us to use γ-glutamyl hydroxymethyl rhodamine green (gGlu-HMRG), a novel fluorophore emitting light at around 520 nm following enzymatic reaction with GGT, as a t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Miyata, Yoichi, Ishizawa, Takeaki, Kamiya, Mako, Yamashita, Suguru, Hasegawa, Kiyoshi, Ushiku, Aya, Shibahara, Junji, Fukayama, Masashi, Urano, Yasuteru, Kokudo, Norihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471246/
https://ncbi.nlm.nih.gov/pubmed/28615696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03760-3
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