A novel liver-specific fluorescent anti-cancer drug delivery system using indocyanine green

Indocyanine green (ICG) accumulates only in hepatocytes and their malignant counterpart, hepatocellular carcinoma (HCC). We have developed ICG-conjugated anti-cancer drugs and noted their significant accumulation in HCC cells both in vitro and in vivo. ICG-conjugated gemcitabine was less toxic to no...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Inagaki, Yoshinori, Kokudo, Takashi, Kamiya, Mako, Uno, Shin-nosuke, Sato, Masumitsu, Kaneko, Junichi, Kokudo, Norihiro, Urano, Yasuteru, Hasegawa, Kiyoshi
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6395603/
https://ncbi.nlm.nih.gov/pubmed/30816163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39269-0
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