Corrective effects of hepatotoxicity by hepatic Dyrk1a gene delivery in mice with intermediate hyperhomocysteinemia

Hyperhomocysteinemia results from hepatic metabolism dysfunction and is characterized by a high plasma homocysteine level, which is also an independent risk factor for cardiovascular disease. Elevated levels of homocysteine in plasma lead to hepatic lesions and abnormal lipid metabolism. Therefore,...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab Rep
Main Authors: Latour, Alizée, Salameh, Sacha, Carbonne, Christel, Daubigney, Fabrice, Paul, Jean-Louis, Kergoat, Micheline, Autier, Valérie, Delabar, Jean-Maurice, De Geest, Bart, Janel, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
SI:Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471159/
https://ncbi.nlm.nih.gov/pubmed/28649528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2014.12.007
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