DYRK1A, a Novel Determinant of the Methionine-Homocysteine Cycle in Different Mouse Models Overexpressing this Down-Syndrome-Associated Kinase

BACKGROUND: Hyperhomocysteinemia, characterized by increased plasma homocysteine level, is associated with an increased risk of atherosclerosis. On the contrary, patients with Down syndrome appear to be protected from the development of atherosclerosis. We previously found a deleterious effect of hy...

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Bibliographic Details
Main Authors: Noll, Christophe, Planque, Chris, Ripoll, Clémentine, Guedj, Fayçal, Diez, Anna, Ducros, Véronique, Belin, Nicole, Duchon, Arnaud, Paul, Jean-Louis, Badel, Anne, de Freminville, Bénédicte, Grattau, Yann, Bléhaut, Henri, Herault, Yann, Janel, Nathalie, Delabar, Jean-Maurice
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760102/
https://ncbi.nlm.nih.gov/pubmed/19844572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007540
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