DYRK1A, a Novel Determinant of the Methionine-Homocysteine Cycle in Different Mouse Models Overexpressing this Down-Syndrome-Associated Kinase

BACKGROUND: Hyperhomocysteinemia, characterized by increased plasma homocysteine level, is associated with an increased risk of atherosclerosis. On the contrary, patients with Down syndrome appear to be protected from the development of atherosclerosis. We previously found a deleterious effect of hy...

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Detalhes bibliográficos
Main Authors: Noll, Christophe, Planque, Chris, Ripoll, Clémentine, Guedj, Fayçal, Diez, Anna, Ducros, Véronique, Belin, Nicole, Duchon, Arnaud, Paul, Jean-Louis, Badel, Anne, de Freminville, Bénédicte, Grattau, Yann, Bléhaut, Henri, Herault, Yann, Janel, Nathalie, Delabar, Jean-Maurice
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760102/
https://ncbi.nlm.nih.gov/pubmed/19844572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007540
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