Clinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer

Precision medicine requires accurate multi-gene clinical diagnostics. We describe the implementation of an Illumina TruSight Tumor (TST) clinical NGS diagnostic framework and parallel validation of a NanoString RNA-based ALK, RET, and ROS1 gene fusion assay for combined analysis of treatment predict...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lindquist, Kajsa Ericson, Karlsson, Anna, Levéen, Per, Brunnström, Hans, Reuterswärd, Christel, Holm, Karolina, Jönsson, Mats, Annersten, Karin, Rosengren, Frida, Jirström, Karin, Kosieradzki, Jaroslaw, Ek, Lars, Borg, Åke, Planck, Maria, Jönsson, Göran, Staaf, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471012/
https://ncbi.nlm.nih.gov/pubmed/28415793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16276
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