Reprogramming induced by isoliquiritigenin diminishes melanoma cachexia through mTORC2-AKT-GSK3β signaling

Isoliquiritigenin (ISL), a member of the flavonoids, is known to have anti-tumor activity in vitro and in vivo. The effect of ISL on reprogramming in cancer cells, however, remains elusive. In this study, we investigated the effect of ISL on reprogramming in human melanoma A375 cells. ISL (15 μg/ml)...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Xiao-Yu, Li, De-Fang, Han, Ji-Chun, Wang, Bo, Dong, Zheng-Ping, Yu, Li-Na, Pan, Zhao-Hai, Qu, Chuan-Jun, Chen, Ying, Sun, Shi-Guo, Zheng, Qiu-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470991/
https://ncbi.nlm.nih.gov/pubmed/28410220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16655
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