Vaccination with Recombinant N-Terminal Domain of Als1p Improves Survival during Murine Disseminated Candidiasis by Enhancing Cell-Mediated, Not Humoral, Immunity

Candida spp. are opportunistic fungal pathogens that are among the most common causes of nosocomial bloodstream infections. The mortality attributable to disseminated candidiasis is 40 to 50% despite antifungal therapy. Clearly, new strategies are needed to prevent this life-threatening infection. B...

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Détails bibliographiques
Auteurs principaux: Ibrahim, Ashraf S., Spellberg, Brad J., Avenissian, Valentina, Fu, Yue, Filler, Scott G., Edwards, John E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Fungal and Parasitic Infections
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC547099/
https://ncbi.nlm.nih.gov/pubmed/15664943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.999-1005.2005
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