The Anti-Candida albicans Vaccine Composed of the Recombinant N Terminus of Als1p Reduces Fungal Burden and Improves Survival in Both Immunocompetent and Immunocompromised Mice

We have previously shown that intraperitoneal vaccination with the recombinant N terminus of Als1p (rAls1p-N) modestly improves survival during murine disseminated candidiasis. We now report marked efficacy with subcutaneous rAls1p-N vaccination. Efficacy is retained in neutropenic and corticosteroi...

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Detalhes bibliográficos
Main Authors: Spellberg, Brad J., Ibrahim, Ashraf S., Avenissian, Valentina, Filler, Scott G., Myers, Carter L., Fu, Yue, Edwards, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231102/
https://ncbi.nlm.nih.gov/pubmed/16113347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.6191-6193.2005
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