Embryonic signature distinguishes pediatric and adult rhabdoid tumors from other SMARCB1-deficient cancers

Extra-cranial rhabdoid tumors (RT) are highly aggressive malignancies of infancy, characterized by undifferentiated histological features and loss of SMARCB1 expression. The diagnosis is all the more challenging that other poorly differentiated cancers lose SMARCB1 expression, such as epithelioid sa...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Richer, Wilfrid, Masliah-Planchon, Julien, Clement, Nathalie, Jimenez, Irene, Maillot, Laetitia, Gentien, David, Albaud, Benoît, Chemlali, Walid, Galant, Christine, Larousserie, Frederique, Boudou-Rouquette, Pascaline, Leruste, Amaury, Chauvin, Celine, Han, Zhi Yan, Coindre, Jean-Michel, Varlet, Pascale, Freneaux, Paul, Ranchère-Vince, Dominique, Delattre, Olivier, Bourdeaut, Franck
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470964/
https://ncbi.nlm.nih.gov/pubmed/28427232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15939
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