Embryonic signature distinguishes pediatric and adult rhabdoid tumors from other SMARCB1-deficient cancers

Extra-cranial rhabdoid tumors (RT) are highly aggressive malignancies of infancy, characterized by undifferentiated histological features and loss of SMARCB1 expression. The diagnosis is all the more challenging that other poorly differentiated cancers lose SMARCB1 expression, such as epithelioid sa...

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Pubblicato in:Oncotarget
Autori principali: Richer, Wilfrid, Masliah-Planchon, Julien, Clement, Nathalie, Jimenez, Irene, Maillot, Laetitia, Gentien, David, Albaud, Benoît, Chemlali, Walid, Galant, Christine, Larousserie, Frederique, Boudou-Rouquette, Pascaline, Leruste, Amaury, Chauvin, Celine, Han, Zhi Yan, Coindre, Jean-Michel, Varlet, Pascale, Freneaux, Paul, Ranchère-Vince, Dominique, Delattre, Olivier, Bourdeaut, Franck
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470964/
https://ncbi.nlm.nih.gov/pubmed/28427232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15939
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