Monoacyl Lipoteichoic Acid from Pneumococci Stimulates Human Cells but Not Mouse Cells

We have developed a method for obtaining pneumococcal lipoteichoic acid (LTA) with none, one, or two acyl chains. Anion-exchange chromatography at pH 9.5 yields pneumococcal LTA (labeled LTA-9.5) that has a mass spectrum identical to that of pre-ion-exchange LTA and loses 500 mass units after deacyl...

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Main Authors: Kim, Je Hak, Seo, Hoseong, Han, Seung Hyun, Lin, Jisheng, Park, Moon-Kook, Sorensen, Uffe B. S., Nahm, Moon H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC547069/
https://ncbi.nlm.nih.gov/pubmed/15664923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.834-840.2005
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