Platelet-Activating Factor-Acetylhydrolase Can Monodeacylate and Inactivate Lipoteichoic Acid

Bacterial lipoteichoic acid (LTA) shares a structural motif with platelet-activating factor (PAF). Both molecules are strong inflammatory agents and have a glycerol backbone with two lipid chains at the sn-1 and sn-2 positions. PAF is normally inactivated by PAF-acetylhydrolase (PAF-AH), a phospholi...

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Autores principales: Seo, Ho Seong, Kim, Je Hak, Nahm, Moon H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
Materias:
Microbial Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459642/
https://ncbi.nlm.nih.gov/pubmed/16603612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.13.4.452-458.2006
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