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Higher oxidative stress in skeletal muscle of McArdle disease patients

McArdle disease (MCD) is an autosomal recessive condition resulting from skeletal muscle glycogen phosphorylase deficiency. The resultant block in glycogenolysis leads to an increased flux through the xanthine oxidase pathway (myogenic hyperuricemia) and could lead to an increase in oxidative stress...

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Bibliografische gegevens
Gepubliceerd in:Mol Genet Metab Rep
Hoofdauteurs: Kaczor, Jan J., Robertshaw, Holly A., Tarnopolsky, Mark A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470535/
https://ncbi.nlm.nih.gov/pubmed/28649515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2017.05.009
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