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Higher oxidative stress in skeletal muscle of McArdle disease patients

McArdle disease (MCD) is an autosomal recessive condition resulting from skeletal muscle glycogen phosphorylase deficiency. The resultant block in glycogenolysis leads to an increased flux through the xanthine oxidase pathway (myogenic hyperuricemia) and could lead to an increase in oxidative stress...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab Rep
Main Authors: Kaczor, Jan J., Robertshaw, Holly A., Tarnopolsky, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470535/
https://ncbi.nlm.nih.gov/pubmed/28649515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2017.05.009
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