Taming Human Genetic Variability: Transcriptomic Meta-Analysis Guides the Experimental Design and Interpretation of iPSC-Based Disease Modeling

Both the promises and pitfalls of the cell reprogramming research platform rest on human genetic variation, making the measurement of its impact one of the most urgent issues in the field. Harnessing large transcriptomics datasets of induced pluripotent stem cells (iPSC), we investigate the implicat...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Germain, Pierre-Luc, Testa, Giuseppe
Format: Artigo
Language:Inglês
Published: Elsevier 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470233/
https://ncbi.nlm.nih.gov/pubmed/28591656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.05.012
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