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Deletion of the SSK1 Response Regulator Gene in Candida albicans Contributes to Enhanced Killing by Human Polymorphonuclear Neutrophils

The isolation and partial functional characterization of the two-component response regulator SSK1 gene of Candida albicans was previously reported. Compared to wild-type (CAF2-1) and gene-reconstituted (SSK23) strains, the ssk1 null strain (SSK21) was avirulent in a murine model of hematogenously d...

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Bibliografiske detaljer
Main Authors: Du, Chen, Calderone, Richard, Richert, John, Li, Dongmei
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC547022/
https://ncbi.nlm.nih.gov/pubmed/15664927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.865-871.2005
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