A Type IV Pilin, PilA, Contributes to Adherence of Burkholderia pseudomallei and Virulence In Vivo

The Burkholderia pseudomallei K96243 genome contains multiple type IV pilin-associated loci, including one encoding a putative pilus structural protein (pilA). A pilA deletion mutant has reduced adherence to human epithelial cells and is less virulent in the nematode model of virulence and the murin...

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Detalhes bibliográficos
Main Authors: Essex-Lopresti, Angela E., Boddey, Justin A., Thomas, Richard, Smith, Martin P., Hartley, M. Gill, Atkins, Timothy, Brown, Nat F., Tsang, Chuk Hai, Peak, Ian R. A., Hill, Jim, Beacham, Ifor R., Titball, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547011/
https://ncbi.nlm.nih.gov/pubmed/15664977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.1260-1264.2005
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