Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis.

Infection of mononuclear cells by human immunodeficiency virus (HIV) begins with binding of the viral envelope glycoprotein, gp120, to its receptor, CD4. CD4 contains four extracellular immunoglobulin-like domains, the first of which (V1) is sufficient for HIV binding. V1 contains three sequences ho...

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Main Authors: Ashkenazi, A, Presta, L G, Marsters, S A, Camerato, T R, Rosenthal, K A, Fendly, B M, Capon, D J
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC54701/
https://ncbi.nlm.nih.gov/pubmed/2402498
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