An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5

The Nucleosome Remodeling and Deacetylase (NuRD) complex is a chromatin regulatory complex that functions as a transcriptional co-repressor in metazoans. The NuRD subunit MBD3 is essential for targeting and assembly of a functional NuRD complex as well as embryonic stem cell (ESC) pluripotency. Thre...

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Udgivet i:Stem Cell Reports
Main Authors: Ee, Ly-Sha, McCannell, Kurtis N., Tang, Yang, Fernandes, Nancy, Hardy, W. Rod, Green, Michael R., Chu, Feixia, Fazzio, Thomas G.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470077/
https://ncbi.nlm.nih.gov/pubmed/28528697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.04.020
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