Programmed mitophagy is essential for the glycolytic switch during cell differentiation

Retinal ganglion cells (RGCs) are the sole projecting neurons of the retina and their axons form the optic nerve. Here, we show that embryogenesis‐associated mouse RGC differentiation depends on mitophagy, the programmed autophagic clearance of mitochondria. The elimination of mitochondria during RG...

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Pubblicato in:EMBO J
Autori principali: Esteban‐Martínez, Lorena, Sierra‐Filardi, Elena, McGreal, Rebecca S, Salazar‐Roa, María, Mariño, Guillermo, Seco, Esther, Durand, Sylvère, Enot, David, Graña, Osvaldo, Malumbres, Marcos, Cvekl, Ales, Cuervo, Ana María, Kroemer, Guido, Boya, Patricia
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470043/
https://ncbi.nlm.nih.gov/pubmed/28465321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695916
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