PppA, a Surface-Exposed Protein of Streptococcus pneumoniae, Elicits Cross-Reactive Antibodies That Reduce Colonization in a Murine Intranasal Immunization and Challenge Model

The multivalent pneumococcal conjugate vaccine is effective against both systemic disease and otitis media caused by serotypes contained in the vaccine. However, serotypes not covered by the present conjugate vaccine may still cause pneumococcal disease. To address these serotypes, and the remaining...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Green, Bruce A., Zhang, Ying, Masi, Amy W., Barniak, Vicki, Wetherell, Michael, Smith, Robert P., Reddy, Molakala S., Zhu, Duzhang
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2005
الموضوعات:
Microbial Immunity and Vaccines
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC547003/
https://ncbi.nlm.nih.gov/pubmed/15664941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.981-989.2005
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