PppA, a Surface-Exposed Protein of Streptococcus pneumoniae, Elicits Cross-Reactive Antibodies That Reduce Colonization in a Murine Intranasal Immunization and Challenge Model

The multivalent pneumococcal conjugate vaccine is effective against both systemic disease and otitis media caused by serotypes contained in the vaccine. However, serotypes not covered by the present conjugate vaccine may still cause pneumococcal disease. To address these serotypes, and the remaining...

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Detalhes bibliográficos
Main Authors: Green, Bruce A., Zhang, Ying, Masi, Amy W., Barniak, Vicki, Wetherell, Michael, Smith, Robert P., Reddy, Molakala S., Zhu, Duzhang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547003/
https://ncbi.nlm.nih.gov/pubmed/15664941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.981-989.2005
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