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Computational Methods for Characterizing Cancer Mutational Heterogeneity

Advances in DNA sequencing technologies have allowed the characterization of somatic mutations in a large number of cancer genomes at an unprecedented level of detail, revealing the extreme genetic heterogeneity of cancer at two different levels: inter-tumor, with different patients of the same canc...

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Bibliographic Details
Published in:Front Genet
Main Author: Vandin, Fabio
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469877/
https://ncbi.nlm.nih.gov/pubmed/28659971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00083
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