Protective and therapeutic effect of felodipine against bleomycin-induced pulmonary fibrosis in mice

Idiopathic pulmonary fibrosis (IPF) involves alveolar epithelial injury and abnormal collagen production caused by activated fibroblasts; transforming growth factor (TGF)-β1 is implicated in this activation. In this study, we screened for chemicals capable of inhibiting TGF-β1-induced collagen produ...

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發表在:Sci Rep
Main Authors: Tanaka, Ken-ichiro, Niino, Tomomi, Ishihara, Tomoaki, Takafuji, Ayaka, Takayama, Takahiro, Kanda, Yuki, Sugizaki, Toshifumi, Tamura, Fumiya, Kurotsu, Shota, Kawahara, Masahiro, Mizushima, Tohru
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469778/
https://ncbi.nlm.nih.gov/pubmed/28611390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03676-y
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