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Idebenone has preventative and therapeutic effects on pulmonary fibrosis via preferential suppression of fibroblast activity

Alveolar epithelial injury induced by reactive oxygen species (ROS) and abnormal collagen production by activated fibroblasts (myofibroblasts) is involved in the onset and exacerbation of idiopathic pulmonary fibrosis (IPF). Compared with alveolar epithelial cells, lung fibroblasts, especially myofi...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Sugizaki, Toshifumi, Tanaka, Ken-ichiro, Asano, Teita, Kobayashi, Daisuke, Hino, Yuuki, Takafuji, Ayaka, Shimoda, Mikako, Mogushi, Kaoru, Kawahara, Masahiro, Mizushima, Tohru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861265/
https://ncbi.nlm.nih.gov/pubmed/31754474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0226-y
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