Bonobos maintain immune-system diversity with three functional types of MHC-B()

Fast-evolving MHC class I polymorphism serves to diversify NK cell and CD8 T cell responses in individuals, families, and populations. As only chimpanzee and bonobo have strict orthologs of all HLA class I, their study gives unique perspective on the human condition. We defined polymorphism of Papa-...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Wroblewski, Emily E., Guethlein, Lisbeth A., Norman, Paul J., Li, Yingying, Shaw, Christiana M., Han, Alex S., Ndjango, Jean-Bosco N., Ahuka-Mundeke, Steve, Georgiev, Alexander V., Peeters, Martine, Hahn, Beatrice H., Parham, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469624/
https://ncbi.nlm.nih.gov/pubmed/28348269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601955
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