A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi

Capitalizing on CRISPR/Cas9 gene-editing techniques and super-resolution nanoscopy, we explore the role of the small GTPase ARF1 in mediating transport steps at the Golgi. Besides its well-established role in generating COPI vesicles, we find that ARF1 is also involved in the formation of long (∼3 µ...

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Publicat a:Mol Biol Cell
Autors principals: Bottanelli, Francesca, Kilian, Nicole, Ernst, Andreas M., Rivera-Molina, Felix, Schroeder, Lena K., Kromann, Emil B., Lessard, Mark D., Erdmann, Roman S., Schepartz, Alanna, Baddeley, David, Bewersdorf, Joerg, Toomre, Derek, Rothman, James E.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2017
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469610/
https://ncbi.nlm.nih.gov/pubmed/28428254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0863
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